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Testosterone therapy: Key to male vitality?

Published On: Feb 24 2014 01:55:16 PM CST
man jogging against blue sky

iStock/Kemter

By Mayo Clinic News Network

The possibilities of testosterone therapy are enticing -- increase your muscle mass, sharpen your memory and concentration, boost your libido, and improve your energy level. As you get older, testosterone therapy may sound like the ultimate anti-aging formula. Yet the health benefits of testosterone therapy for age-related decline in testosterone aren't as clear as they may seem. Find out what's known -- and not known -- about testosterone therapy for normal aging.

What is testosterone?

Testosterone is a hormone produced primarily in the testicles. Testosterone helps maintain men's:

  • Bone density
  • Fat distribution
  • Muscle strength and mass
  • Red blood cell production
  • Sex drive
  • Sperm production

Hypogonadism is a disease in which the body is unable to produce normal amounts of testosterone due to a problem with the testicles or with the pituitary gland that controls the testicles. Testosterone replacement therapy can improve the signs and symptoms of low testosterone in these men. Doctors may prescribe testosterone as injections, pellets, patches or gels.

What happens to testosterone levels with age?

Testosterone peaks during adolescence and early adulthood. As you get older, your testosterone level gradually declines -- typically about 1 percent a year after age 30. It is important to determine in older men if a low testosterone level is simply due to the decline of normal aging or if it is due to a disease (hypogonadism).

Does a naturally declining testosterone level cause the signs and symptoms of aging?

Not necessarily. Men can experience many signs and symptoms as they age, and some may occur as a result of lower testosterone levels and can include:

  • Changes in sexual function. This may include reduced sexual desire, fewer spontaneous erections -- such as during sleep -- and infertility.
  • Changes in sleep patterns. Sometimes low testosterone causes insomnia or other sleep disturbances.
  • Physical changes. Various physical changes are possible, including increased body fat, reduced muscle bulk and strength, and decreased bone density. Swollen or tender breasts (gynecomastia) and hair loss are possible. You may experience hot flashes and have less energy than you used to.
  • Emotional changes. Low testosterone may contribute to a decrease in motivation or self-confidence. You may feel sad or depressed, or have trouble concentrating or remembering things.

It's important to note that some of these signs and symptoms are a normal part of aging. Others can be caused by various underlying factors, including medication side effects, thyroid problems, depression and excessive alcohol use. A blood test is the only way to diagnose a low testosterone level.

Source: http://www.mayoclinic.org/testosterone-therapy/ART-20045728/